Watch this presentation by Dr Praveen Pathak (5 October 2016) exploring the role white cells play and their impact within safe blood transfusion; their effect on recipients' immune response, ability to transmit disease as well as their clinical utility in specific circumstances.

Learning outcomes:

• Understand physiology issues with white cells when transfused- the possibility of disease transmission and recipient immune responses.
  
• Explain the rationale for Leucodepletion and implications  for patients.
  
• Understand the mechanism for TRIM- Transfusion related immunomodulation.
• State when and why Granulocyte transfusions are clinically required.
  

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